Naoki Ohtsu
Hokkaido University, Japan
Biography
Naoki Otsu is interested in stem cell biology and tumorigenesis from stem cells. Based on Cancer stem cell theory, we are searching for cells with high tumorigenicity and membrane proteins intensely expressed in the cells. Currently, we focus on glioblastoma, a malignant brain tumor, and analyze membrane proteins that are molecular targets of antibody drugs. Using induced cancer stem cells derived from neural stem cells as model cells, strongly expressed membrane proteins were searched for multiple candidate proteins. This presentation introduces the molecules whose function and molecular mechanism are clarified among the obtained candidate.
Abstract
Abstract : Inhibition of Eva1 degrade the formation and development of glioblastomas